Portrayed by Tessa Thompson, Bianca suffers from progressive hearing loss who uses a hearing aid and there is no information about Bianca's upbringing or family life. She resides in Philadelphia, Pennsylvania where she meets Adonis Creed.
Bianca is an upcoming singer that lives in Philadelphia and downstairs to Adonis. They met when Donnie confronts her about the music being too loud. The next meeting between them, Bianca takes Donnie to restaurant where they strike up a conversation and Bianca tells Adonis, she might go completely deaf at one point, and is learning sign language just in case. Bianca begins a relationship with Adonis when they kissed on her living room floor. Their relationships get strained when Bianca finds out Adonis is Apollo Creed's son, but they reconcile and she also convinces Adonis to use his father name when he fights. After Adonis had a fight at one of Bianca's music concerts, the couple broke up and they got back together when a former heavyweight champion named Rocky Balboa (Adonis' trainer) had cancer where she attended Donnie's fights with Leo Sporino and Ricky Conlan.
Bianca's music career kicks off with a recording contract, relationship with Adonis get stronger after Adonis proposes to her and they become engaged. When Adonis decides to fight Viktor Drago (Ivan Drago's son), Bianca moves to Los Angeles with him where she discovers that she is pregnant. During her pregnancy, Bianca develops a strong bond with Mary Anne Creed (Adonis' mother) as Mary Anne gives Bianca advice on how to deal with Adonis' depression. Bianca gives birth to a baby girl named Amara Creed, but it is discovered that Amara is born deaf due to Bianca's progressive degenerative hearing disorder being hereditary. Bianca sings during Adonis opening to the ring and embraces him after he win. She is last seen with Adonis and Amara at Apollo's grave.