Ventimiglia was born in Orange County, California, the son of Carol née Wilson ) and Peter Ventimiglia. His father is of Sicilian descent and his mother has English, Irish, Scottish, French, and Cherokee Indian ancestry. His last name, Ventimiglia, meaning "twenty miles", is the name of the town of Ventimiglia in Liguria, Italy, which later gave its name to another city, Ventimiglia di Sicilia. The youngest of three children, he has two older sisters, Leslie and Laurel. He has explained in an interview with USA Today that his "crooked mouth" is a result of dead nerves on the left side, which cause that side to remain immobile, much like, incidentally, actor Sylvester Stallone, with whom he worked in Rocky Balboa.
- "– Milo Ventimiglia – Yahoo!TV". Tv.yahoo.com. 1977-07-08. http://tv.yahoo.com/milo-ventimiglia/contributor/38190. Retrieved 2011-07-04.
- http://www.tvguide.com/celebrities/milo-ventimiglia/166819 – Milo Ventimiglia News, Milo Ventimiglia Bio and Photos | TVGuide.com
- Keck, William (2006-12-18). "Yo! Ventimiglia gets into the tough-guy act". USA Today. http://www.usatoday.com/life/people/2006-12-18-milo-ventimiglia_x.htm. Retrieved 2006-12-21.
- Ventimiglia, Milo (2002-05-14). "Milo Ventimiglia AOL Chat". AOL. http://asianfanatics.net/forum/lofiversion/index.php/t21610.html. Retrieved 2007-11-04.
- Milo Ventimiglia at the Internet Movie Database